HSC Cell Imaging Core
The HSC Cell Imaging Core, with over 20 years of experience, consistently delivers exceptional services to researchers within and beyond the University of Utah, as well as catering to corporate clients seeking access to cutting-edge optical microscopes and advanced imaging analysis software.
As a result of strong and continuous support from both the University and our dedicated users, the HSC Cell Imaging Core has expanded to five major locations across the campus. Each year, more than 300 researchers can readily access our extensive array of over 15 standard and state-of-the-art instruments. We offer comprehensive training for independent instrument use and also provide Assisted Imaging services through our team of experienced core members. In addition, we enthusiastically engage in deep collaborations to assist with complex projects.
We kindly request that patrons acknowledge the HSC Cell Imaging Core in their publications whenever experimental data is generated using our core instruments. This recognition serves to underscore the impact of your work and highlights the vital contributions that the Cell Imaging Core makes. It also plays a crucial role in our efforts to secure grants and funding for acquiring equipment that benefits our user community.
Available Services
Major Instruments
— Pending —
Service Rates
Facilities
- HSC – Health Science Center – Building 585
- Office Phone Number: 801-587-7964
- Offices
- Room 48a – Xiang Wang
- Room 48e – Anton Classen, Bill James
- HCI – Huntsman Cancer Institute – Building 555
- Office Phone Number: 801-585-0106
- Office Room Number: 1460
- CSC – Crocker Science Center – Building 5
- Office Phone Number: 801-587-0313
- Office Room Number: 30
Requesting Services
To request services with our facility please use the Cores Resource Scheduling System by clicking on the “Resource” link on the top bar. This system is cores wide and uses the campus uNID system. Upon first login you will be asked for information and for which PI there is an authorized chartfield registered with the cores office. If you have problems logging in contact billing at billing@cores.utah.edu
If you have never used our services before you will be required to fill out a Work Authorization Form which can be accessed by clicking on the appropriate button below. After your work authorization has been approved you will be able to login to the resource system
Training Types
There are two tracks of training offered by the Cell Imaging Core
New Users (20 hours or less per year)
- Assisted Imaging
- Staff will image your samples exclusively with you. Your presence is required for an assessment consultation of your sample quality and image goals.
- Signature of a release form is required to ensure the quality of samples and the resulting images
- Acknowledgement in publications for the University of Utah Cell Imaging is a requirement for this type of extensive assistance
Long Term Users
- Patrons that prefer in depth training for skill development with the goal of imaging yourself and to obtain rigorous understanding of software.
- Advanced training series
- Project consultation and basic training
- Advanced training for special software implementation (FRET, FRAP, live cell imaging, stitching, time lapse, ect.. )
Documentation
Before working with us, please take the time to read our Microscopy Core Policies and Training Documentation located below.
Cell Imaging Documentation / Training Server Booking Procedure Guide Resource System User Guide
Xiang Wang
Cell Imaging Facility Director
Bill James
Microscopist
Anton Classen
Research Associate Microcopist
Please submit all inquiries regarding GCF Services to the Department of Historical Inaccuracies via un-trained carrier pigeon guided by sunflower seed trail to the Laurentian Fan. Any correspondence not accompanied by a pigeon will be fed to the compost pile on suspicion of being mis-information.
Citing Our Facility
Acknowledgments
We would like to thank you for acknowledging the our facility. This recognition allows us to highlight the impact of your work and demonstrates the important contributions of our facility makes to research across the University of Utah. The recognition our core receives from your acknowledgments also aids in receiving grants and further funding for equipment and services we can provide to our users.
Self-Run Services / Instrumentation Usage:
In published papers that used instruments at our facility and notably involved staff members please use the following format:
“We acknowledge (facility name) at the University of Utah for use of equipment (insert instrument/service details here), and thank (insert any notable staff member – if desired) for their assistance.”
Assisted Services:
In published papers where a staff member assisted you in addition to the requested services please use the following format:
“We acknowledge (facility name) at the University of Utah for use of equipment (insert instrument/service details here), and thank (insert staff member-required) for their assistance in (service provided).”
Collaboration:
For publications resulting from collaborations that assisted with the methodologies, planning process and execution of your experiment in addition to equipment usage we require Co-author attribution on your publication for our facility and any staff members who provided substantial contributions to the originating project.
Recent Acknowledgements
- Almanzar, D. E., Gordon, S. G., Bristow, C., Hamrick, A., von Diezmann, L., Liu, H., & Rog, O. (2023). Meiotic DNA exchanges in C. elegans are promoted by proximity to the synaptonemal complex. Life Science Alliance, 6(4), e202301906. https://doi.org/10.26508/lsa.202301906
- Anderl, W. J., Pearson, N., Converse, M. I., Yu, S. M., & Monson, K. L. (2023). Strain-induced collagen denaturation is rate dependent in failure of cerebral arteries. Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2023.04.032
- Ellis, K. E., Smihula, H., Ganguly, I., Vigato, E., Bervoets, S., Auer, T. O., Benton, R., Litwin-Kumar, A., & Caron, S. J. C. (2023). Evolution of connectivity architecture in the Drosophila mushroom body [Preprint]. Neuroscience. https://doi.org/10.1101/2023.02.10.528036
- Eshima, H., Shahtout, J. L., Siripoksup, P., Pearson, M. J., Mahmassani, Z. S., Ferrara, P. J., Lyons, A. W., Maschek, J. A., Peterlin, A. D., Verkerke, A. R. P., Johnson, J. M., Salcedo, A., Petrocelli, J. J., Miranda, E. R., Anderson, E. J., Boudina, S., Ran, Q., Cox, J. E., Drummond, M. J., & Funai, K. (2023). Lipid hydroperoxides promote sarcopenia through carbonyl stress. ELife, 12, e85289. https://doi.org/10.7554/eLife.85289
- Espino-Sanchez, T. J., Wienkers, H., Marvin, R. G., Nalder, S.-A., García-Guerrero, A. E., VanNatta, P. E., Jami-Alahmadi, Y., Mixon Blackwell, A., Whitby, F. G., Wohlschlegel, J. A., Kieber-Emmons, M. T., Hill, C. P., & Sigala, P. A. (2023). Direct tests of cytochrome c and c1 functions in the electron transport chain of malaria parasites. Proceedings of the National Academy of Sciences of the United States of America, 120(19), e2301047120. https://doi.org/10.1073/pnas.2301047120
- Ferrara, P. J., Reidy, P. T., Petrocelli, J. J., Yee, E. M., Fix, D. K., Mahmassani, Z. S., Montgomery, J. A., McKenzie, A. I., de Hart, N. M. M. P., & Drummond, M. J. (2023). Global deletion of CCL2 has adverse impacts on recovery of skeletal muscle fiber size and function and is muscle-specific. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.00444.2022
- Hagen-Lillevik, S., Johnson, J., & Lai, K. (2022). Early postnatal alterations in follicular stress response and survival in a mouse model of Classic Galactosemia. Journal of Ovarian Research, 15(1), 122. https://doi.org/10.1186/s13048-022-01049-2
- Hagen-Lillevik, S., Johnson, J., Siddiqi, A., Persinger, J., Hale, G., & Lai, K. (2022). Harnessing the Power of Purple Sweet Potato Color and Myo-Inositol to Treat Classic Galactosemia. International Journal of Molecular Sciences, 23(15), 8654. https://doi.org/10.3390/ijms23158654
- He, Y., Anderson, B., Hu, Q., Hayes, R. B., Huff, K., Isaacson, J., Warner, K. S., Hauser, H., Greenberg, M., Chandra, V., Kauser, K., & Berceli, S. A. (2023). Photochemically Aided Arteriovenous Fistula Creation to Accelerate Fistula Maturation. International Journal of Molecular Sciences, 24(8), Article 8. https://doi.org/10.3390/ijms24087571
- Hoffman, L. M., Jensen, C. C., & Beckerle, M. C. (2022). Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility. Molecular Biology of the Cell, 33(11), ar100. https://doi.org/10.1091/mbc.E22-02-0057
- Kidwell, C. U., Casalini, J. R., Pradeep, S., Scherer, S. D., Greiner, D., Bayik, D., Watson, D. C., Olson, G. S., Lathia, J. D., Johnson, J. S., Rutter, J., Welm, A. L., Zangle, T. A., & Roh-Johnson, M. (2023). Transferred mitochondria accumulate reactive oxygen species, promoting proliferation. ELife, 12, e85494. https://doi.org/10.7554/eLife.85494
- LaJoie, D., Turkmen, A. M., Mackay, D. R., Jensen, C. C., Aksenova, V., Niwa, M., Dasso, M., & Ullman, K. S. (2022). A role for Nup153 in nuclear assembly reveals differential requirements for targeting of nuclear envelope constituents. Molecular Biology of the Cell, 33(13), ar117. https://doi.org/10.1091/mbc.E22-05-0189
— Pending —
Oversight Committee
| Name | Department |
| Bruce Edgar, Chair | Oncological Sciences |
| James Cox, Ph.D., HSC Cores Director | Cores Research Facilities |
| Alex Shcheglovitov, Assistant Professor | Neurobiology and Anatomy |
| Mark Smith, Research Assistant Professor | Oncological Sciences |
| Markus Babst, Professor | Biological Sciences |
| Michelle Mendoza, Associate Professor | Oncological Sciences |
| Minna Roh-Johnson, Assistant Professor | Department of Biochemistry |
| Sophie Caron, Assistant Professor | Biological Sciences |
| Gabrielle Kardon, Professor | Human Genetics |