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HSC Cell Imaging Core

The HSC Cell Imaging Core, with over 20 years of experience, consistently delivers exceptional services to researchers within and beyond the University of Utah, as well as catering to corporate clients seeking access to cutting-edge optical microscopes and advanced imaging analysis software.

As a result of strong and continuous support from both the University and our dedicated users, the HSC Cell Imaging Core has expanded to five major locations across the campus. Each year, more than 300 researchers can readily access our extensive array of over 15 standard and state-of-the-art instruments. We offer comprehensive training for independent instrument use and also provide Assisted Imaging services through our team of experienced core members. In addition, we enthusiastically engage in deep collaborations to assist with complex projects.

We kindly request that patrons acknowledge the HSC Cell Imaging Core in their publications whenever experimental data is generated using our core instruments. This recognition serves to underscore the impact of your work and highlights the vital contributions that the Cell Imaging Core makes. It also plays a crucial role in our efforts to secure grants and funding for acquiring equipment that benefits our user community.

New Users
Booking

Welcome to Cell Imaging News!

Check out the latest from the Cell Imaging core. There is a lot of cool stuff happening here!
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News & Announcements

Dear Core Users, Our Cell Imaging Core has recently acquired an additional Imaris 3D Imaging Analysis Software license, allowing up to two users to access the software simultaneously from our...

 

Dear Core Users,   We want to invite you to an exclusive opportunity to gain hands-on experience with the state-of-the-art Echo Spinning Disk Confocal Microscope.   This session is designed to...

 

Dear Core Users, Campus will be hosting an upcoming lunch and seminar event – Uncovering biological mechanisms: from single molecules to single cells, with Trey Simpson, PhD.  “We will present...

 

Dear Users, At the start of the new year, all researchers who utilize the instruments we have available through the Cell Imaging Core will have to sign an updated Cell...

 

Dear Users, We are pleased to announce Nikon will be demonstrating their latest confocal microscope. Some Key Features: Nikon AX R MP confocal microscope has super-resolution imaging capabilities. NSPARC detector - The...

 

Dear Users, the Cell Imaging Core staff has received your feedback, and we are happy to announce shorter lead time when scheduling resources!  Now, you can schedule, delete, and modify...

 

Dear Users, We at HSC Cell Imaging Cores Facility are so excited to have seen how successful the Andor's (Oxford Instruments) all-in-one fluorescence, confocal, and super-resolution BC43 microscope Launch &...

 

Dear Users, I am pleased to announce that Andor (Oxford Instruments) will be demonstrating its All-in-One fluorescence, confocal, and super-resolution microscope, along with the Imaris 3D analysis software, from September...

 

Zeiss Axioscan 7 is ready to use, get ready for some awesome demos, and more in this month's newsletter.

 

We are excited to introduce some new team members as we bid farewell to another. We have a new slide scanner coming. The Nikon A1R is back online. And check...

 

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Stay Informed

Keep up to date with our quarterly newsletters & other exciting updates.

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UU Microscopy List

Note: Unsubscribing from the list above does not effect messages originating from the Cores Resource System.

Instruments Available

  • Zeiss LSM 700 Confocal Microscope
  • EVOS M5000
  • Zeiss Axioscan.Z1 Slide Scanner
  • Nikon Eclipse Ti Widefield Microscope
  • Leica SP8 Confocal Microscope with a White Light Laser
  • Leica SP8 Confocal Microscope
  • Zeiss Axioscan 7 Slide Scanner
  • Zeiss 880 Airy Scan Confocal Microscope
  • STEDYCON Super-Resolution Microscope
  • Olympus FV1000 Confocal Microscope
  • Leica Spinning Disk Confocal with VisiView Software
  • DeltaVision Ulta Widefield Microscope
  • Nikon Spinning Disk Confocal Microscope with Ring-TIRF module
  • Nikon N-STORM
  • Leica Cryostat
  • Workstation: Imaris
  • Workstation: Nikon Elements AR
  • Workstation: Zeiss ZEN Desk
  • CosMx Spatial Molecular Imager
  • Nikon N-STORM Microscope

Service Rates

Instruments and workstations can be booked at any time.  Bookings can only be cancelled or modified at least 12 hours in advance of the session start time.  Booked time has to be used otherwise. To schedule a training or consultation session with a Cell Imaging staff member, a 24-hour lead time is required.  Please contact the Cell Imaging staff directly if you need to adjust your scheduling on shorter notice.

Cell Imaging Core Policies Agreement

Cell Imaging Core Policies AgreementDownload

Requesting Services

If you are new to the Cores, you must complete a work authorization form through the Work Authorization System prior to requesting services. Work authorizations may be used for any services offered by facilities managed by HSC Cores. After your work authorization has been approved you will be able to login to the Resource System.

Existing users may login directly to the Resource Scheduling System to schedule or order services. This system is cores-wide and uses University of Utah uNID authentication.

Work Authorization
System On Campus / UU
Work Authorization
System Off Campus / Business
Resource Scheduling
System

If you encounter financial/account issues, contact the Cores Admin office.
For technical issues with any of the web applications, contact the developers.

Charge Rates Procedure /
Federal Facilities and Administration (F&A) Rate

Part of the University’s agreement with the Federal Government regarding F&A is that the University will not offer a lower than F&A rate to other kinds of sponsors. That means that the University has to use, at minimum, the same rates for commercial sponsors as it does for the Federal Government. The University would jeopardize its relationship with the Federal Government (the University’s single largest sponsor) if it were to accept rates lower than the current federal F&A rate.

The current F&A Rate is: 54%

The facility internal rate is used when exclusively internal funding sources are used. The F&A / external academic rate applies when external funding sources are used i.e. Federal Government or other academic universities. For more information about F&A rates at the University of Utah please see: 6.3 Indirect Costs/Facilities and Administrative Costs (F&A)

Process to Become an HSC Cell Imaging Core User:

  1. Register as a Core Member: Complete the online Work Authorization Form. 
  2. Complete Laser Safety Training: complete the training module and email the certificate to Cell Imaging Support. 
  3. Sign the Cell Imaging Core Policies Agreement: Read and sign the Cell Imaging Core Policies Agreement and email it to Cell Imaging Support. 
  4. Complete Consultation: Fill out the Patron Consultation Form and schedule a 30-minute consultation with one of the core members via Core Resources Scheduling. A ZOOM meeting will be held.  
  5. Subscribe to the Email List: Join the mailing list to receive important updates and event notifications. 
  6. Book the Instrument and Core Member’s Calendar for initial Training: Simultaneously book the instrument and a core member’s calendar for 2 hours for your first training. Use the Core Resources Scheduling system.  (Need help? Instructional video here.) 
  7. Refresher Training: Users who haven’t used the core instruments for over six months or have prior experience must book a 1-hour refresher training. 
  8. Access to the Room: Core members will assist trained users in accessing the room after training. 
  9. Book the Calendar: Schedule time to start using the core instruments. 
  10. 24-Hour Lead Time: A 24-hour lead time is required to book a core member’s calendar. 
  11. Last-Minute Booking: Last-minute bookings are allowed for instrument calendars. 
  12. Cancellation Policy: Schedules cannot be canceled or modified within 12 hours of the experiment’s start time. 
  13. Acknowledge the Core Instrument: If published data is generated using core instruments, acknowledge the Core Instrument. Check the “Publications” tab for details.
Profile

Xiang Wang

Facility Director

Contact

Anton Classen

Research Assoc. Microscopist

Contact

Satoshi Komatsu

Research Assoc. Microscopist

Contact

Katherine Siebeneck

Lab Specialist

Contact

Facilities

HSC - Health Science Center - Building 585 - MAP

Offices: 48A, 48E, 55
Labs: 48B, 48D, 54, 56, 60
Phone Number: 801-587-7964

HCI - Huntsman Cancer Institute North - Building 555 - MAP

Offices: 1460
Labs: 1430, 1440, 1470 1480
Phone Number: 801-585-0106

CSC - Crocker Science Center - Building 5 - MAP

Offices: 030
Labs: 032

EEJ - Jones Medical Research - Building 565 - MAP

Labs: 3532, 5100, 5122

ASB - Skaggs Biology Building - Building 82 - MAP

Labs: 230

Hours of Operation

9:00 am to 5:00 pm
Monday - Friday

Contact Email
Cell Imaging Support

Mailing Address

Cell Imaging
Old Skaggs, Bldg 582
30 S 2000 E, Rm 250
Salt Lake City, UT  84112

Citing Our Facility

Acknowledgments

We would like to thank you for acknowledging the our facility. This recognition allows us to highlight the impact of your work and demonstrates the important contributions of our facility makes to research across the University of Utah. The recognition our core receives from your acknowledgments also aids in receiving grants and further funding for equipment and services we can provide to our users.

Self-Run Services / Instrumentation Usage:

In published papers that used instruments at our facility and notably involved staff members please use the following format:

We acknowledge (facility name) at the University of Utah for use of equipment (insert instrument/service details here), and thank (insert any notable staff member – if desired) for their assistance.

Assisted Services:

In published papers where a staff member assisted you in addition to the requested services please use the following format:

We acknowledge (facility name) at the University of Utah for use of equipment (insert instrument/service details here), and thank (insert staff member-required) for their assistance in (service provided).

Collaboration:

For publications resulting from collaborations that assisted with the methodologies, planning process and execution of your experiment in addition to equipment usage we require Co-author attribution on your publication for our facility and any staff members who provided substantial contributions to the originating project.

All Publications

2023

  • Anderl, W. J., Pearson, N., Converse, M. I., Yu, S. M., & Monson, K. L. (2023). Strain-induced collagen denaturation is rate dependent in failure of cerebral arteries. Acta Biomaterialia, 164, 282–292. https://doi.org/10.1016/j.actbio.2023.04.032
  • Anderson, B., Blair, D., Huff, K., Wisniewski, J., Warner, K. S., & Kauser, K. (2023). Photochemical Modification of the Extracellular Matrix to Alter the Vascular Remodeling Process. Journal of Functional Biomaterials, 14(12), Article 12. https://doi.org/10.3390/jfb14120566
  • Carney, K. R., Khan, A. M., Stam, S., Samson, S. C., Mittal, N., Han, S. J., Bidone, T. C., & Mendoza, M. C. (2023a). Nascent adhesions shorten the period of lamellipodium protrusion through the Brownian ratchet mechanism. Molecular Biology of the Cell, mbc.E23-08-0314. https://doi.org/10.1091/mbc.E23-08-0314
  • Carney, K. R., Khan, A. M., Stam, S., Samson, S. C., Mittal, N., Han, S. J., Bidone, T. C., & Mendoza, M. C. (2023b). Nascent adhesions shorten the period of lamellipodium protrusion through the Brownian ratchet mechanism. Molecular Biology of the Cell, 34(12), ar115. https://doi.org/10.1091/mbc.E23-08-0314
  • Chiola, S., Yang, J., Ullah, H. M. A., Napan, K., Huang, Q., Gamboa, N., Youssef, O., Colman, H., Cheshier, S. H., & Shcheglovitov, A. (2023). Transcriptional changes consistent with altered neuronal differentiation, angiogenesis, and tumor plasticity induced in human subpallial telencephalic organoid-glioblastoma chimeras (p. 2023.05.11.540229). bioRxiv. https://doi.org/10.1101/2023.05.11.540229
  • de Hart, N. M. M. P., Petrocelli, J. J., Nicholson, R. J., Yee, E. M., van Onselen, L., Lang, M. J., Bourrant, P.-E., Ferrara, P. J., Bastian, E. D., Ward, L. S., Petersen, B. L., & Drummond, M. J. (2023). Dietary delivery of glycomacropeptide within the whey protein matrix is not effective in mitigating tissue ceramide deposition and obesity in high fat fed mice. Journal of Dairy Science. https://doi.org/10.3168/jds.2023-23914
  • de Hart, N. MMP., Petrocelli, J. J., Nicholson, R. J., Yee, E. M., Ferrara, P. J., Bastian, E. D., Ward, L. S., Petersen, B. L., Summers, S. A., & Drummond, M. J. (2023). Palmitate-Induced Inflammation and Myotube Atrophy in C2C12 Cells Are Prevented by the Whey Bioactive Peptide, Glycomacropeptide. The Journal of Nutrition, 153(10), 2915–2928. https://doi.org/10.1016/j.tjnut.2023.08.033
  • Digal, L., Samson, S., Stevens, M., Ghorai, A., Kim, H., Mifflin, M., Carney, K., Williamson, D., Um, S., Nagy, G., Oh, D.-C., Mendoza, M., & Roberts, A. (2023). Non-threaded isomers of sungsanpin and ulleungdin lasso peptides inhibit H1299 cancer cell migration [Preprint]. Chemistry. https://doi.org/10.26434/chemrxiv-2023-cfnrh
  • Ellis, K. E., Bervoets, S., Smihula, H., Ganguly, I., Vigato, E., Auer, T. O., Benton, R., Litwin-Kumar, A., & Caron, S. J. C. (2023). Evolution of connectivity architecture in the Drosophila mushroom body (p. 2023.02.10.528036). bioRxiv. https://doi.org/10.1101/2023.02.10.528036
  • Figueroa, K. P., Gross, C., Atienza, E. B., Paul, S., Gandelman, M., Haack, T., Kakar, N., Sturm, M., Casadei, N., Admard, J., Park, J., Zühlke, C., Hellenbroich, Y., Pozojevic, J., Balachandran, S., Händler, K., Zittel, S., Timmann, D., Erdlenbruch, F., … Pulst, S. M. (2023). GGC expansion in ZFHX3 causes SCA4 and impairs autophagy (p. 2023.10.26.23297560). medRxiv. https://doi.org/10.1101/2023.10.26.23297560
  • Guo, L., Jacob, S., Manne, B. K., Kolawole, E. M., Guo, S., Wang, X., Murray, D., Tugolukova, E. A., Portier, I., Kosaka, Y., Barba, C., Rondina, M. T., Evavold, B., Morley, C., Bhatlekar, S., & Bray, P. F. (2023). Actin-bundling protein L-plastin promotes megakaryocyte rigidity and dampens proplatelet formation. Haematologica, 109(1), 331–336. https://doi.org/10.3324/haematol.2023.283016
  • Nagarajan N, Capecchi MR. Optogenetic stimulation of mouse Hoxb8 microglia in specific regions of the brain induces anxiety, grooming, or both. Mol Psychiatry. 2023 Apr 10;. doi: 10.1038/s41380-023-02019-w. [Epub ahead of print] PubMed PMID: 37037872.
  • Paine, E. L., Skalicky, J. J., Whitby, F. G., Mackay, D. R., Ullman, K. S., Hill, C. P., & Sundquist, W. I. (2023). The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission. eLife, 12, e84515. https://doi.org/10.7554/eLife.84515
  • Petrocelli, J. J., McKenzie, A. I., de Hart, N. M. M. P., Reidy, P. T., Mahmassani, Z. S., Keeble, A. R., Kaput, K. L., Wahl, M. P., Rondina, M. T., Marcus, R. L., Welt, C. K., Holland, W. L., Funai, K., Fry, C. S., & Drummond, M. J. (2023). Disuse-induced muscle fibrosis, cellular senescence, and senescence-associated secretory phenotype in older adults are alleviated during re-ambulation with metformin pre-treatment. Aging Cell, n/a(n/a), e13936. https://doi.org/10.1111/acel.13936
  • Scherer, S. D., Zhao, L., Butterfield, A. J., Yang, C.-H., Cortes-Sanchez, E., Guillen, K. P., Welm, B. E., & Welm, A. L. (2023). Breast cancer PDxO cultures for drug discovery and functional precision oncology. STAR Protocols, 4(3), 102402. https://doi.org/10.1016/j.xpro.2023.102402
  • Van Scoyk, A. N., Antelope, O., Franzini, A., Ayer, D. E., Peterson, R. T., Pomicter, A. D., Owen, S. C., & Deininger, M. W. (2023). Bioluminescence Assay of Lysine Deacylase Sirtuin Activity. bioRxiv, 2023.08.10.552871. https://doi.org/10.1101/2023.08.10.552871

2024

  • Carey, C. M., Hollins, H. L., Schmid, A. V., & Gagnon, J. A. (2024). Distinct features of the regenerating heart uncovered through comparative single-cell profiling. Biology Open, 13(4), bio060156. https://doi.org/10.1242/bio.060156
  • Casey, M. J., Chan, P. P., Li, Q., Jette, C. A., Kohler, M., Myers, B. R., & Stewart, R. A. (2024). A Simple and Scalable Zebrafish Model of Sonic Hedgehog Medulloblastoma (p. 2024.02.03.577834). bioRxiv. https://doi.org/10.1101/2024.02.03.577834
  • Collins, B. C., Shapiro, J. B., Scheib, M. M., Musci, R. V., Verma, M., & Kardon, G. (2024). Three-dimensional imaging studies in mice identify cellular dynamics of skeletal muscle regeneration. Developmental Cell. https://doi.org/10.1016/j.devcel.2024.03.017
  • de Hart, N. M. M. P., Petrocelli, J. J., Nicholson, R. J., Yee, E. M., van Onselen, L., Lang, M. J., Bourrant, P.-E., Ferrara, P. J., Bastian, E. D., Ward, L. S., Petersen, B. L., & Drummond, M. J. (2024). Dietary delivery of glycomacropeptide within the whey protein matrix is not effective in mitigating tissue ceramide deposition and obesity in mice fed a high-fat diet. Journal of Dairy Science, 107(2), 669–682. https://doi.org/10.3168/jds.2023-23914
  • Fennel, Z. J., Bourrant, P.-E., Kurian, A. S., Petrocelli, J. J., de Hart, N. M. M. P., Yee, E. M., Boudina, S., Keirstead, H. S., Nistor, G., Greilach, S. A., Berchtold, N. C., Lane, T. E., & Drummond, M. J. (2024). Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice. Aging Cell, n/a(n/a), e14144. https://doi.org/10.1111/acel.14144
  • Figueroa, K. P., Gross, C., Buena-Atienza, E., Paul, S., Gandelman, M., Kakar, N., Sturm, M., Casadei, N., Admard, J., Park, J., Zühlke, C., Hellenbroich, Y., Pozojevic, J., Balachandran, S., Händler, K., Zittel, S., Timmann, D., Erdlenbruch, F., Herrmann, L., … Pulst, S. M. (2024). A GGC-repeat expansion in ZFHX3 encoding polyglycine causes spinocerebellar ataxia type 4 and impairs autophagy. Nature Genetics, 1–10. https://doi.org/10.1038/s41588-024-01719-5
  • Herstine, J. A., Chang, P.-K., Chornyy, S., Stevenson, T. J., Sunshine, A. C., Nokhrina, K., Rediger, J., Wentz, J., Vetter, T. A., Scholl, E., Holaway, C., Pyne, N. K., Bratasz, A., Yeoh, S., Flanigan, K. M., Bonkowsky, J. L., & Bradbury, A. M. (2024). Evaluation of safety and early efficacy of AAV gene therapy in mouse models of vanishing white matter disease. Molecular Therapy: The Journal of the American Society of Gene Therapy, S1525-0016(24)00212-0. https://doi.org/10.1016/j.ymthe.2024.03.034
  • Merrill, C. B., Titos, I., Pabon, M. A., Montgomery, A. B., Rodan, A. R., & Rothenfluh, A. (2024). Iterative assay for transposase-accessible chromatin by sequencing to isolate functionally relevant neuronal subtypes. Science Advances, 10(13), eadi4393. https://doi.org/10.1126/sciadv.adi4393
  • Morales, J. C. F., Redfearn, C., Titus, M. A., & Roh-Johnson, M. (2024). Reduced PaxillinB localization to cell-substrate adhesions promotes cell migration in Dictyostelium (p. 2024.03.19.585764). bioRxiv. https://doi.org/10.1101/2024.03.19.585764
  • Moriwaki, M., Liu, L., James, E. R., Tolley, N., O’Connora, A. M., Emery, B., Aston, K. I., Campbell, R. A., & Welt, C. K. (2024). Heterozygous Eif4nif1 Stop Gain Mice Replicate the Primary Ovarian Insufficiency Phenotype in Women (p. 2024.04.09.588694). bioRxiv. https://doi.org/10.1101/2024.04.09.588694
  • Nwagbo, U., Parvez, S., Maschek, J. A., & Bernstein, P. S. (2024). Elovl4b knockout zebrafish as a model for ocular very-long-chain PUFA deficiency. Journal of Lipid Research, 65(3). https://doi.org/10.1016/j.jlr.2024.100518
  • Smith, J. J., Valentino, T. R., Ablicki, A. H., Banerjee, R., Colligan, A. R., Eckert, D. M., Desjardins, G. A., & Diehl, K. L. (2024). A genetically-encoded fluorescent biosensor for visualization of acetyl-CoA in live cells (p. 2023.12.31.573774). bioRxiv. https://doi.org/10.1101/2023.12.31.573774
  • Verma, S., Giagnocavo, S. D., Curtin, M. C., Arumugam, M., Osburn-Staker, S. M., Wang, G., Atkinson, A., Nix, D. A., Lum, D. H., Cox, J. E., & Hilgendorf, K. I. (2024). Zinc Alpha-2-Glycoprotein (ZAG/AZGP1) secreted by triple-negative breast cancer promotes tumor microenvironment fibrosis (p. 2024.03.04.583349). bioRxiv. https://doi.org/10.1101/2024.03.04.583349
  • Walker, M. F., Zhang, J., Steiner, W., Ku, P.-I., Zhu, J.-F., Michaelson, Z., Yen, Y.-C., Lee, A., Long, A. B., Casey, M. J., Poddar, A., Nelson, I. B., Arveseth, C. D., Nagel, F., Clough, R., LaPotin, S., Kwan, K. M., Schulz, S., Stewart, R. A., … Myers, B. R. (2024). GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade (p. 2023.05.10.540226). bioRxiv. https://doi.org/10.1101/2023.05.10.540226
  • Wallis, G. J., Bell, L. A., Wagner, J. N., Buxton, L., Balachandar, L., & Wilcox, K. S. (2024). Reactive microglia fail to respond to environmental damage signals in a viral-induced mouse model of temporal lobe epilepsy (p. 2024.03.06.583768). bioRxiv. https://doi.org/10.1101/2024.03.06.583768

2022

  • Hagen-Lillevik, S., Johnson, J., & Lai, K. (2022). Early postnatal alterations in follicular stress response and survival in a mouse model of Classic Galactosemia. Journal of Ovarian Research, 15(1), 122. https://doi.org/10.1186/s13048-022-01049-2
  • Hagen-Lillevik, S., Johnson, J., Siddiqi, A., Persinger, J., Hale, G., & Lai, K. (2022). Harnessing the Power of Purple Sweet Potato Color and Myo-Inositol to Treat Classic Galactosemia. International Journal of Molecular Sciences, 23(15), 8654. https://doi.org/10.3390/ijms23158654
  • Hoffman, L. M., Jensen, C. C., & Beckerle, M. C. (2022). Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility. Molecular Biology of the Cell, 33(11), ar100. https://doi.org/10.1091/mbc.E22-02-0057
  • LaJoie, D., Turkmen, A. M., Mackay, D. R., Jensen, C. C., Aksenova, V., Niwa, M., Dasso, M., & Ullman, K. S. (2022). A role for Nup153 in nuclear assembly reveals differential requirements for targeting of nuclear envelope constituents. Molecular Biology of the Cell, 33(13), ar117. https://doi.org/10.1091/mbc.E22-05-0189
  • Rush, C. M., Blanchard, Z., Polaski, J. T., Osborne, K. S., Osby, K., Vahrenkamp, J. M., Yang, C.-H., Lum, D. H., Hagan, C. R., Leslie, K. K., Pufall, M. A., Thiel, K. W., & Gertz, J. (2022). Characterization of HCI-EC-23 a novel estrogen- and progesterone-responsive endometrial cancer cell line. Scientific Reports, 12(1), Article 1. https://doi.org/10.1038/s41598-022-24211-8
  • Sefton, E. M., Gallardo, M., Tobin, C. E., Collins, B. C., Colasanto, M. P., Merrell, A. J., & Kardon, G. (2022). Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm. ELife, 11, e74592. https://doi.org/10.7554/eLife.74592
  • Simeone, C. A., Wilkerson, J. L., Poss, A. M., Banks, J. A., Varre, J. V., Guevara, J. L., Hernandez, E. J., Gorsi, B., Atkinson, D. L., Turapov, T., Frodsham, S. G., Morales, J. C. F., O’Neil, K., Moore, B., Yandell, M., Summers, S. A., Krolewski, A. S., Holland, W. L., & Pezzolesi, M. G. (2022). A dominant negative ADIPOQ mutation in a diabetic family with renal disease, hypoadiponectinemia, and hyperceramidemia. Npj Genomic Medicine, 7(1), Article 1. https://doi.org/10.1038/s41525-022-00314-z
  • Smith, M. A., Blankman, E., Jensen, C. C., Hoffman, L. M., Ullman, K. S., & Beckerle, M. C. (2022). Nuclear pore complexes concentrate on Actin/LINC/Lamin nuclear lines in response to mechanical stress in a SUN1 dependent manner. Heliyon, 8(12), e12147. https://doi.org/10.1016/j.heliyon.2022.e12147
  • Wang, Y., Chiola, S., Yang, G., Russell, C., Armstrong, C. J., Wu, Y., Spampanato, J., Tarboton, P., Ullah, H. M. A., Edgar, N. U., Chang, A. N., Harmin, D. A., Bocchi, V. D., Vezzoli, E., Besusso, D., Cui, J., Cattaneo, E., Kubanek, J., & Shcheglovitov, A. (2022). Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes. Nature Communications, 13(1), Article 1. https://doi.org/10.1038/s41467-022-33364-z
  • Wenzel, D. M., Mackay, D. R., Skalicky, J. J., Paine, E. L., Miller, M. S., Ullman, K. S., & Sundquist, W. I. (2022). Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission. ELife, 11, e77779. https://doi.org/10.7554/eLife.77779
  • Zhang, C., Jin, Y., Marchetti, M., Lewis, M. R., Hammouda, O. T., & Edgar, B. A. (2022). EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation. Current Biology. https://doi.org/10.1016/j.cub.2022.07.003

2023

  • Almanzar, D. E., Gordon, S. G., Bristow, C., Hamrick, A., von Diezmann, L., Liu, H., & Rog, O. (2023). Meiotic DNA exchanges in C. elegans are promoted by proximity to the synaptonemal complex. Life Science Alliance, 6(4), e202301906. https://doi.org/10.26508/lsa.202301906
  • Anderl, W. J., Pearson, N., Converse, M. I., Yu, S. M., & Monson, K. L. (2023). Strain-induced collagen denaturation is rate dependent in failure of cerebral arteries. Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2023.04.032
  • Ellis, K. E., Smihula, H., Ganguly, I., Vigato, E., Bervoets, S., Auer, T. O., Benton, R., Litwin-Kumar, A., & Caron, S. J. C. (2023). Evolution of connectivity architecture in the Drosophila mushroom body [Preprint]. Neuroscience. https://doi.org/10.1101/2023.02.10.528036
  • Eshima, H., Shahtout, J. L., Siripoksup, P., Pearson, M. J., Mahmassani, Z. S., Ferrara, P. J., Lyons, A. W., Maschek, J. A., Peterlin, A. D., Verkerke, A. R. P., Johnson, J. M., Salcedo, A., Petrocelli, J. J., Miranda, E. R., Anderson, E. J., Boudina, S., Ran, Q., Cox, J. E., Drummond, M. J., & Funai, K. (2023). Lipid hydroperoxides promote sarcopenia through carbonyl stress. ELife, 12, e85289. https://doi.org/10.7554/eLife.85289
  • Espino-Sanchez, T. J., Wienkers, H., Marvin, R. G., Nalder, S.-A., García-Guerrero, A. E., VanNatta, P. E., Jami-Alahmadi, Y., Mixon Blackwell, A., Whitby, F. G., Wohlschlegel, J. A., Kieber-Emmons, M. T., Hill, C. P., & Sigala, P. A. (2023). Direct tests of cytochrome c and c1 functions in the electron transport chain of malaria parasites. Proceedings of the National Academy of Sciences of the United States of America, 120(19), e2301047120. https://doi.org/10.1073/pnas.2301047120
  • Ferrara, P. J., Reidy, P. T., Petrocelli, J. J., Yee, E. M., Fix, D. K., Mahmassani, Z. S., Montgomery, J. A., McKenzie, A. I., de Hart, N. M. M. P., & Drummond, M. J. (2023). Global deletion of CCL2 has adverse impacts on recovery of skeletal muscle fiber size and function and is muscle-specific. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.00444.2022
  • He, Y., Anderson, B., Hu, Q., Hayes, R. B., Huff, K., Isaacson, J., Warner, K. S., Hauser, H., Greenberg, M., Chandra, V., Kauser, K., & Berceli, S. A. (2023). Photochemically Aided Arteriovenous Fistula Creation to Accelerate Fistula Maturation. International Journal of Molecular Sciences, 24(8), Article 8. https://doi.org/10.3390/ijms24087571
  • Kidwell, C. U., Casalini, J. R., Pradeep, S., Scherer, S. D., Greiner, D., Bayik, D., Watson, D. C., Olson, G. S., Lathia, J. D., Johnson, J. S., Rutter, J., Welm, A. L., Zangle, T. A., & Roh-Johnson, M. (2023). Transferred mitochondria accumulate reactive oxygen species, promoting proliferation. ELife, 12, e85494. https://doi.org/10.7554/eLife.85494
  • Merrill, C. B., Titos, I., Pabon, M. A., Montgomery, A. B., Rodan, A. R., & Rothenfluh, A. (2023). Iterative assay for transposase-accessible chromatin by sequencing to isolate functionally relevant neuronal subtypes (p. 2023.04.14.536950). bioRxiv. https://doi.org/10.1101/2023.04.14.536950
  • Petrocelli, J. J., Hart, N. M. M. P. de, Lang, M. J., Yee, E. M., Ferrara, P. J., Fix, D. K., Chaix, A., Funai, K., & Drummond, M. J. (2023). Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail. Aging, 15. https://doi.org/10.18632/aging.204600
  • Preston, A. J., Rogers, A., Sharp, M., Mitchell, G., Toruno, C., Barney, B. B., Donovan, L. N., Bly, J., Kennington, R., Payne, E., Iovino, A., Furukawa, G., Robinson, R., Shamloo, B., Buccilli, M., Anders, R., Eckstein, S., Fedak, E. A., Wright, T., … Abegglen, L. M. (2023). Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria. Cell Death Discovery, 9(1), Article 1. https://doi.org/10.1038/s41420-023-01348-7
  • Rice, M. C., Little, J. H., Forrister, D. L., Machado, J., Clark, N. L., & Gagnon, J. A. (2023). Gadusol is a maternally provided sunscreen that protects fish embryos from DNA damage [Preprint]. Developmental Biology. https://doi.org/10.1101/2023.01.30.526370
  • Stover, J. D., Trone, M. A., Lawrence, B., & Bowles, R. D. (2023). Multiplex epigenome editing of ion channel expression in nociceptive neurons abolished degenerative IVD-conditioned media-induced mechanical sensitivity. JOR SPINE, n/a(n/a), e1253. https://doi.org/10.1002/jsp2.1253
  • Su, G., Farhat, R., Laxman, A. K., Chapman-Natewa, K., Nelson, I. E., & Chan, O. (2023). Astrocyte glycogen is a major source of hypothalamic lactate in rats with recurrent hypoglycemia. Diabetes, db220902. https://doi.org/10.2337/db22-0902
  • Warde, K. M., Smith, L. J., Liu, L., Stubben, C. J., Lohman, B. K., Willett, P. W., Ammer, J. L., Castaneda-Hernandez, G., Imodoye, S. O., Zhang, C., Jones, K. D., Converso-Baran, K., Ekiz, H. A., Barry, M., Clay, M. R., Kiseljak-Vassiliades, K., Giordano, T. J., Hammer, G. D., & Basham, K. J. (2023). Senescence-induced immune remodeling facilitates metastatic adrenal cancer in a sex-dimorphic manner. Nature Aging, 1–20. https://doi.org/10.1038/s43587-023-00420-2
  • Xue, Q., Varady, S. R. S., Waddell, T. Q. A., Roman, M. R., Carrington, J., & Roh-Johnson, M. (2023). Lack of Paxillin phosphorylation promotes single-cell migration in vivo. The Journal of Cell Biology, 222(3), e202206078. https://doi.org/10.1083/jcb.202206078

2021

  • Fadul, J., Zulueta-Coarasa, T., Slattum, G. M., Redd, N. M., Jin, M. F., Redd, M. J., Daetwyler, S., Hedeen, D., Huisken, J., & Rosenblatt, J. (2021). KRas-transformed epithelia cells invade and partially dedifferentiate by basal cell extrusion. Nat Commun, 12(1), 7180. doi:10.1038/s41467-021-27513-z
  • Falekun, S., Sepulveda, J., Jami-Alahmadi, Y., Park, H., Wohlschlegel, J. A., & Sigala, P. A. (2021). Divergent acyl carrier protein decouples mitochondrial Fe-S cluster biogenesis from fatty acid synthesis in malaria parasites. Elife, 10. doi:10.7554/eLife.71636
  • Ferrara, P. J., Verkerke, A. R. P., Maschek, J. A., Shahtout, J. L., Siripoksup, P., Eshima, H., Johnson, J. M., Petrocelli, J. J., Mahmassani, Z. S., Green, T. D., McClung, J. M., Cox, J. E., Drummond, M. J., & Funai, K. (2021). Low lysophosphatidylcholine induces skeletal muscle myopathy that is aggravated by high-fat diet feeding. Faseb Journal, 35(10). doi:10.1096/fj.202101104R
  • Fix, D. K., Ekiz, H. A., Petrocelli, J. J., Mckenzie, A. M., Mahmassani, Z. S., O'Connell, R. M., & Drummond, M. J. (2021). Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy. Aging Cell, 20(9). doi:10.1111/acel.13448
  • Fix, D. K., Mahmassani, Z. S., Petrocelli, J. J., de Hart, N. M. M. P., Ferrara, P. J., Painter, J. S., Nistor, G., Lane, T. E., Keirstead, H. S., & Drummond, M. J. (2021). Reversal of deficits in aged skeletal muscle during disuse and recovery in response to treatment with a secrotome product derived from partially differentiated human pluripotent stem cells. Geroscience, 43(6), 2635-2652. doi:10.1007/s11357-021-00423-0
  • Happ, J. T., Arveseth, C. D., Bruystens, J., Bertinetti, D., Nelson, I. B., Olivieri, C., Hedeen, D. S., Zhu, J.-F., Capener, J. L., Bröckel, J. W., Vu, L., King, C. C., Ruiz-Perez, V. L., Veglia, G., Herberg, F. W., Taylor, S. S., & Myers, B. R. (2021). A PKA Inhibitor Motif within Smoothened Controls Hedgehog Signal Transduction. bioRxiv. doi:10.1101/2021.07.05.451193
  • Kidwell, C. U., Casalini, J. R., Pradeep, S., Scherer, S. D., Greiner, D., Johnson, J. S., Olson, G. S., Rutter, J., Welm, A. L., Zangle, T. A., & Roh-Johnson, M. (2021). Laterally transferred macrophage mitochondria act as a signaling source promoting cancer cell proliferation. bioRxiv. doi:10.1101/2021.08.10.455713
  • Kursel, L. E., Cope, H. D., & Rog, O. (2021). Unconventional conservation reveals structure-function relationships in the synaptonemal complex. Elife, 10. doi:10.7554/eLife.72061
  • Lai, S. A., Gundlapalli, H., Ekiz, H. A., Jiang, A., Fernandez, E., & Welm, A. L. (2021). Blocking Short-Form Ron Eliminates Breast Cancer Metastases through Accumulation of Stem-Like CD4(+) T Cells That Subvert Immunosuppression. Cancer Discovery, 11(12), 3178-3197. doi:10.1158/2159-8290.CD-20-1172
  • Liu, H., Gordon, S. G., & Rog, O. (2021). Heterologous synapsis in C. elegans is regulated by meiotic double-strand breaks and crossovers. Chromosoma, 130(4), 237-250. doi:10.1007/s00412-021-00763-y
  • Marchetti, M., Zhang, C., & Edgar, B. A. (2021). An improved organ explant culture method reveals stem cell lineage dynamics in the adult Drosophila intestine. bioRxiv. doi:10.1101/2021.12.17.473114
  • Mathew, B., Aoyagi, K. L., & Fisher, M. A. (2021). Yersinia pestis Lipopolysaccharide Remodeling Confers Resistance to a Xenopsylla cheopis Cecropin. Acs Infectious Diseases, 7(8), 2536-2545. doi:10.1021/acsinfecdis.1c00275
  • Nicholson, R. J., Poss, A. M., Maschek, J. A., Cox, J. E., Hopkins, P. N., Hunt, S. C., Playdon, M. C., Holland, W. L., & Summers, S. A. (2021). Characterizing a Common CERS2 Polymorphism in a Mouse Model of Metabolic Disease and in Subjects from the Utah CAD Study. Journal of Clinical Endocrinology & Metabolism, 106(8), E3098-E3109. doi:10.1210/clinem/dgab155
  • Ost, K. S., O'Meara, T. R., Stephens, W. Z., Chiaro, T., Zhou, H., Penman, J., Bell, R., Catanzaro, J. R., Song, D., Singh, S., Call, D. H., Hwang-Wong, E., Hanson, K. E., Valentine, J. F., Christensen, K. A., O'Connell, R. M., Cormack, B., Ibrahim, A. S., Palm, N. W., Noble, S. M., & Round, J. L. (2021). Adaptive immunity induces mutualism between commensal eukaryotes. Nature, 596(7870), 114-118. doi:10.1038/s41586-021-03722-w
  • Petrocelli, J. J., Mahmassani, Z. S., Fix, D. K., Montgomery, J. A., Reidy, P. T., McKenzie, A. I., de Hart, N. M, Ferrara, P. J., Kelley, J. J., Eshima, H., Funai, K., & Drummond, M. J. (2021). Metformin and leucine increase satellite cells and collagen remodeling during disuse and recovery in aged muscle. Faseb Journal, 35(9). doi:10.1096/fj.202100883R
  • Rheinemann, L., Downhour, D. M., Bredbenner, K., Mercenne, G., Davenport, K. A., Schmitt, P. T., Necessary, C. R., McCullough, J., Schmitt, A. P., Simon, S. M., Sundquist, W. I., & Elde, N. C. (2021). RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis. Cell, 184(21), 5419-5431.e16. doi:10.1016/j.cell.2021.09.008
  • Tamamouna, V., Rahman, M. M., Petersson, M., Charalambous, I., Kux, K., Mainor, H., Bolender, V., Isbilir, B., Edgar, B. A., & Pitsouli, C. (2021). Remodelling of oxygen-transporting tracheoles drives intestinal regeneration and tumorigenesis in Drosophila. Nat Cell Biol, 23(5), 497-510. doi:10.1038/s41556-021-00674-1
  • Zhang, P., Katzaroff, A. J., Buttitta, L. A., Ma, Y., Jiang, H., Nickerson, D. W., Øvrebø, J. I., & Edgar, B. A. (2021). The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1. Proc Natl Acad Sci U S A, 118(7). doi:10.1073/pnas.2015675118

2022

  • Batot, G., Metcalf, C., Bell, L., Pauletti, A., Wilcox, K., & Bröer, S. (2022). A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus. Journal of Visualized Experiments. doi:10.3791/63673
  • Cho, J. M., Park, S., Kwon, O. S., La Salle, D. T., Cerbie, J., Fermoyle, C. C., Morgan, D., Nelson, A., Bledsoe, A., Bharath, L. P., Tandar, M., Kunapuli, S. P., Richardson, R. S., Anandh Babu, P. V., Mookherjee, S., Kishore, B. K., Wang, F., Yang, T., Boudina, S., Trinity, J. D., & Symons, J. D. (2022). Activating P2Y1 receptors improves function in arteries with repressed autophagy. Cardiovascular Research. doi:10.1093/cvr/cvac061
  • Figueroa, K., Anderson, C. J., Paul, S., Dansithong, W., Gandelman, M., Scoles, D. R., & Pulst, S. M. (2022). Slc9a6 mutation causes Purkinje cell loss and ataxia in the shaker rat. bioRxiv. doi:10.1101/2022.03.28.486143
  • Guillen, K. P., Fujita, M., Butterfield, A. J., Scherer, S. D., Bailey, M. H., Chu, Z., DeRose, Y. S., Zhao, L., Cortes-Sanchez, E., Yang, C. H., Toner, J., Wang, G., Qiao, Y., Huang, X., Greenland, J. A., Vahrenkamp, J. M., Lum, D. H., Factor, R. E., Nelson, E. W., Matsen, C. B., Poretta, J. M., Rosenthal, R., Beck, A. C., Buys, S. S., Vaklavas, C., Ward, J. H., Jensen, R. L., Jones, K. B., Li, Z., Oesterreich, S., Dobrolecki, L. E., Pathi, S. S., Woo, X. Y., Berrett, K. C., Wadsworth, M. E., Chuang, J. H., Lewis, M. T., Marth, G. T., Gertz, J., Varley, K. E., Welm, B. E., & Welm, A. L. (2022). A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology. Nat Cancer, 3(2), 232-250. doi:10.1038/s43018-022-00337-6
  • Hill, J. H., Massaquoi, M. S., Sweeney, E. G., Wall, E. S., Jahl, P., Bell, R., Kallio, K., Derrick, D., Murtaugh, L. C., Parthasarathy, R., Remington, S. J., Round, J. L., & Guillemin, K. (2022). A microbiota membrane disrupter disseminates to the pancreas and increases β-cell mass. bioRxiv. doi:10.1101/2022.03.24.485696
  • Ingram, K., Samson, S. C., Zewdu, R., Zitnay, R. G., Snyder, E. L., & Mendoza, M. C. (2022). NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity. Oncogene, 41(2), 293-300. doi:10.1038/s41388-021-02076-x
  • Jensen, O., Trivedi, S., Meier, J. D., Fairfax, K. C., Hale, J. S., & Leung, D. T. (2022). A subset of follicular helper-like MAIT cells can provide B cell help and support antibody production in the mucosa. Science Immunology, 7(67). doi:10.1126/sciimmunol.abe8931
  • Kaur, K., Mohammadpour, R., Ghandehari, H., Reilly, C. A., Paine, R., & Kelly, K. E. (2022). Effect of combustion particle morphology on biological responses in a Co-culture of human lung and macrophage cells. Atmospheric Environment, 284, 119194. doi:10.1016/j.atmosenv.2022.119194
  • Kaur, K., Mohammadpour, R., Sturrock, A., Ghandehari, H., Reilly, C., Paine, R., & Kelly, K. E. (2022). Comparison of biological responses between submerged, pseudo-air-liquid interface, and air-liquid interface exposure of A549 and differentiated THP-1 co-cultures to combustion-derived particles. Journal of Environmental Science and Health, Part A, 1-12. doi:10.1080/10934529.2022.2083429
  • LaBelle, S. A., Dinkins, S. S., Hoying, J. B., Budko, E. V., Rauff, A., Strobel, H. A., Lin, A. H., & Weiss, J. A. (2022). Matrix anisotropy promotes angiogenesis in a density-dependent manner. Am J Physiol Heart Circ Physiol, 322(5), H806-H818. doi:10.1152/ajpheart.00072.2022
  • Lam, G., Beebe, K., & Thummel, C. S. (2022). A direct-drive GFP reporter for studies of tracheal development in. Fly (Austin), 16(1), 105-110. doi:10.1080/19336934.2022.2030191
  • Lin, Y., Perovanovic, J., Kong, Y., Igyarto, B. Z., Zurawski, S., Tantin, D., Zurawski, G., Bettini, M., & Bettini, M. L. (2022). Antibody-Mediated Targeting of a Hybrid-Insulin-Peptide Towards Neonatal Thymic Langerin+ Cells Enhances T Cell Central Tolerance and Delays Autoimmune Diabetes. Diabetes. doi:10.2337/db21-1069
  • McKenzie, A. I., Mahmassani, Z. S., Petrocelli, J. J., de Hart, N. M. M. P., Fix, D. K., Ferrara, P. J., LaStayo, P. C., Marcus, R. L., Rondina, M. T., Summers, S. A., Johnson, J. M., Trinity, J. D., Funai, K., & Drummond, M. J. (2022). Short-term exposure to a clinical dose of metformin increases skeletal muscle mitochondrial H2O2 emission and production in healthy, older adults: A randomized controlled trial. Experimental gerontology, 163, 111804. doi:10.1016/j.exger.2022.111804
  • Meng, F., Fleming, B. A., Jia, X., Rousek, A. A., Mulvey, M. A., & Ward, D. M. (2022). Lysosomal iron recycling in mouse macrophages is dependent upon both LcytB and Steap3 reductases. Blood Adv, 6(6), 1692-1707. doi:10.1182/bloodadvances.2021005609
  • Nie, X., Munyoki, S. K., Sukhwani, M., Schmid, N., Missel, A., Emery, B. R., DonorConnect, Stukenborg, J., Mayerhofer, A., Orwig, K. E., Aston, K. I., Hotaling, J. M., Cairns, B. R., & Guo, J. (2022). Single-cell analysis of human testis aging and correlation with elevated body mass index. Developmental Cell, 57(9), 1160-1176.e5. doi:10.1016/j.devcel.2022.04.004
  • Okada, M., Rajaram, K., Swift, R. P., Mixon, A., Maschek, J. A., Prigge, S. T., & Sigala, P. A. (2022). Critical role for isoprenoids in apicoplast biogenesis by malaria parasites. Elife, 11. doi:10.7554/eLife.73208
  • Øvrebø, J. I., Bradley-Gill, M., Zielke, N., Kim, M., Marchetti, M., Bohlen, J., Lewis, M., van Straaten, M., Moon, N., & Edgar, B. A. (2022). Translational control of E2f1 regulates the Drosophila cell cycle. Proc Natl Acad Sci U S A, 119(4). doi:10.1073/pnas.2113704119
  • Van Deren, D. A., De, S., Xu, B., Eschenbacher, K. M., Zhang, S., & Capecchi, M. R. (2022). Defining the Hoxb8 cell lineage during murine definitive hematopoiesis. Development, 149(8). doi:10.1242/dev.200200
  • Wenzel, D. M., Mackay, D. R., Skalicky, J. J., Paine, E. L., Miller, M. S., Ullman, K. S., & Sundquist, W. I. (2022). Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission. bioRxiv. doi:10.1101/2022.02.09.477148
  • Wojtalewicz, S., Vizmeg, J., Erickson, S., Lade, C., Shea, J., Sant, H., Magda, J., Gale, B., Agarwal, J., & Davis, B. (2022). Evaluating the influence of particle morphology and density on the viscosity and injectability of a novel long-acting local anesthetic suspension. J Biomater Appl. doi:10.1177/08853282221106486
  • Xue, Q., Varady, S. R. S., Waddell, T. Q. A., Carrington, J., & Roh-Johnson, M. (2022). Focal adhesion-based cell migration is differentially regulated in vivo versus in vitro by Paxillin phosphorylation. bioRxiv. doi:10.1101/2022.03.02.482703
  • Yang, G., Parker, E., Gorsi, B., Liebowitz, M., Maguire, C., King, J. B., Coon, H., Lopez-Larson, M., Anderson, J., Yandell, M., & Shcheglovitov, A. (2022). Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatric bipolar disorder. medRxiv. doi:10.1101/2022.05.06.22274499
  • Zhao, H., Pomicter, A. D., Eiring, A. M., Franzini, A., Ahmann, J., Hwang, J.-Y., Senina, A., Helton, B., Iyer, S., Yan, D., Khorashad, J. S., Zabriskie, M. S., Agarwal, A., Redwine, H. M., Bowler, A. D., Clair, P. M., McWeeney, S. K., Druker, B. J., Tyner, J. W., Stirewalt, D. L., Oehler, V. G., Varambally, S., Berrett, K. C., Vahrenkamp, J. M., Gertz, J., Varley, K. E., Radich, J. P., & Deininger, M. W. (2022). MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis. Blood, 139(5), 761–778. doi:10.1182/blood.2021011802

2020

  • Ahmed, S., Maldera, J., Krunic, D., Paiva-Silva, G., Penalva, C., Teleman, A., & Edgar, B. (2020). Fitness trade-offs incurred by ovary-to-gut steroid signalling in Drosophila. Nature, 584(7821), 415-+. doi:10.1038/s41586-020-2462-y
  • Auer, T. O., Khallaf, M. A., Silbering, A. F., Zappia, G., Ellis, K., Álvarez-Ocaña, R., Arguello, J. R., Hansson, B. S., Jefferis, G. S. X.E, Caron, S. J. C., Knaden, M., & Benton, R. (2020). Olfactory receptor and circuit evolution promote host specialization. Nature, 579(7799), 402-408. doi:10.1038/s41586-020-2073-7
  • Bell, L. A., Wallis, G. J., & Wilcox, K. S. (2020). Reactivity and increased proliferation of NG2 cells following central nervous system infection with Theiler's murine encephalomyelitis virus. J Neuroinflammation, 17(1), 369. doi:10.1186/s12974-020-02043-5
  • Bhatlekar, S., Manne, B. K., Basak, I., Edelstein, L. C., Tugolukova, E., Stoller, M. L., Cody, M. J., Morley, S. C., Nagalla, S., Weyrich, A. S., Rowley, J. W., O'Connell, R. M.,Rondina, M. T., Campbell, R. A., & Bray, P. F. (2020). miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin. Blood, 136(15), 1760-1772. doi:10.1182/blood.2020005230
  • Davis, B., Erickson, S., Wojtalewicz, S., Simpson, A., Metcalf, C., Sant, H., Shea, J., Gale, B., & Agarwal, J. (2020). Entrapping bupivacaine-loaded emulsions in a crosslinked-hydrogel increases anesthetic effect and duration in a rat sciatic nerve block model. International Journal of Pharmaceutics, 588. doi:10.1016/j.ijpharm.2020.119703
  • Dong, Z. M., Lin, E., Wechsler, M. E., Weller, P. F., Klion, A. D., Bochner, B. S., Delker, D. A., Hazel, M. W., Fairfax, K., Khoury, P., Akuthota, P., Merkel, P. A., Dyer, A. M., Langford, C., Specks, U., Gleich, G. J., Chinchilli, V. M., Raby, B., Yandell, M., & Clayton, F.  (2020). Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features. Am J Pathol, 190(7), 1438-1448. doi:10.1016/j.ajpath.2020.03.005
  • Eshima, H., Siripoksup, P., Mahmassani, Z., Johnson, J., Ferrara, P., Verkerke, A., Salcedo, A., Drummond, M.J., & Funai, K. (2020). Neutralizing mitochondrial ROS does not rescue muscle atrophy induced by hindlimb unloading in female mice. Journal of Applied Physiology, 129(1), 124-132. doi:10.1152/japplphysiol.00456.2019
  • Hoffman, L. M., Smith, M. A., Jensen, C. C., Yoshigi, M., Blankman, E., Ullman, K. S., & Beckerle, M. C. (2020). Mechanical stress triggers nuclear remodeling and the formation of transmembrane actin nuclear lines with associated nuclear pore complexes. Mol Biol Cell, 31(16), 1774-1787. doi:10.1091/mbc.E19-01-0027
  • Keefe, M. D., Soderholm, H. E., Shih, H. Y., Stevenson, T. J., Glaittli, K. A., Bowles, D. M., Scholl, E., Colby, S., Merchant, S., Hsu, E. W., & Bonkowsky, J. L.  (2020). Vanishing white matter disease expression of truncated EIF2B5 activates induced stress response. Elife, 9. doi:10.7554/eLife.56319
  • Li, J., Mahoney, B. D., Jacob, M. S., & Caron, S. J. C. (2020). Visual Input into the Drosophila melanogaster Mushroom Body. Cell Rep, 32(11), 108138. doi:10.1016/j.celrep.2020.108138
  • Okada, M., Guo, P., Nalder, S. A., & Sigala, P. A. (2020). Doxycycline has distinct apicoplast-specific mechanisms of antimalarial activity. Elife, 9. doi:10.7554/eLife.60246
  • Strobel, H. A., LaBelle, S. A., Krishnan, L., Dale, J., Rauff, A., Poulson, A. M., Bader, N., Beare, J. E., Aliaj, K., Weiss, J. A., & Hoying, J. B. (2020). Stromal Cells Promote Neovascular Invasion Across Tissue Interfaces. Front Physiol, 11, 1026. doi:10.3389/fphys.2020.01026

2021

  • de Hart, N. M. M.P.,Mahmassani, Z. S.,Reidy, P. T.,Kelley, J. J.,McKenzie, A. I.,Petrocelli, J. J.,Bridge, M. J.,Baird, L. M.,Bastian, E. D.,Ward, L. S.,Howard, M. T., & Drummond, M. J. (2021). Acute Effects of Cheddar Cheese Consumption on Circulating Amino Acids and Human Skeletal Muscle. Nutrients, 13(2). doi:10.3390/nu13020614
  • Derksen, A., Shih, H.-Y., Forget, D., Darbelli, L., Tran, L. T., Poitras, C., . . . Bernard, G. (2021). Variants in LSM7 impair LSM complexes assembly, neurodevelopment in zebrafish and may be associated with an ultra-rare neurological disease. Human Genetics and Genomics Advances, 2(3), 100034. doi:https://doi.org/10.1016/j.xhgg.2021.100034
  • Ferrara, P. J., Rong, X., Maschek, J. A., Verkerke, A. R., Siripoksup, P., Song, H., Green, T. D., Krishnan, K. C., Johnson, J. M., Turk, J., Houmard, J. A., Lusis, A. J., Drummond, M. J., McClung, J. M., Cox, J. E., Shaikh, S. R., Tontonoz, P., Holland, W. L., & Funai, K. (2021). Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle. J Clin Invest, 131(8). doi:10.1172/JCI135963
  • Ferrari, L., Pei, J., Zickella, M., Rey, C., Zickella, J., Ramirez, A., & Taylor, N. (2021). D2 Receptors in the Periaqueductal Gray/Dorsal Raphe Modulate Peripheral Inflammatory Hyperalgesia via the Rostral Ventral Medulla. Neuroscience, 463, 159-173. doi:10.1016/j.neuroscience.2021.03.035
  • Grow, E. J., Weaver, B. D., Smith, C. M., Guo, J., Stein, P., Shadle, S. C., Hendrickson, P. G., Johnson, N. E., Butterfield, R. J., Menafra, R., Kloet, S. L., van der Maarel, S. M., Williams, C. J., & Cairns, B. R. (2021). p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models. Nat Genet. doi:10.1038/s41588-021-00893-0
  • Lewis, M. (2021). Signaling Pathway Regulation of Transcription Factor E2F1 Alters Cell Cycle Progression in Drosophila Midgut. In B. Edgar & J. I. Øvrebø (Eds.), (Vol. 21). Undergraduate Research Journal: University of Utah.
  • Lyu, Y., Verma, V. K., Lee, Y., Taleb, I., Badolia, R., Shankar, T. S., Kyriakopoulos, C. P., Selzman, C. H., Caine, W., Alharethi, R., Navankasattusas, S., Seidel, T., Drakos, S. G., & Sachse, F. B. (2021). Remodeling of t-system and proteins underlying excitation-contraction coupling in aging versus failing human heart. NPJ Aging Mech Dis, 7(1), 16. doi:10.1038/s41514-021-00066-7
  • Mahmassani, Z. S., McKenzie, A. I., Petrocelli, J. J., de Hart, N. M., Reidy, P. T., Fix, D. K., Ferrara, P. J., Funai, K., & Drummond, M. J. (2021). Short-term metformin ingestion by healthy older adults improves myoblast function. Am J Physiol Cell Physiol, 320(4), C566-C576. doi:10.1152/ajpcell.00469.2020
  • Mathew, B., Aoyagi, K. L., & Fisher, M. A. (2021). Yersinia pestis lipopolysaccharide remodeling confers resistance to a Xenopsylla cheopis cecropin. bioRxiv, 2021.2003.2012.435208. doi:10.1101/2021.03.12.435208
  • Moriwaki, M., & Welt, C. K. (2021). PRL Mutation Causing Alactogenesis: Insights Into Prolactin Structure and Function Relationships. J Clin Endocrinol Metab, 106(8), e3021-e3026. doi:10.1210/clinem/dgab201
  • Russell, K. L., Downie, J. M., Gibson, S. B., Tsetsou, S., Keefe, M. D., Duran, J. A., Figueroa, K. P., Bromberg, M. B., Murtaugh, L. C., Bonkowsky, J. L., Pulst, S. M., & Jorde, L. B. (2021). Pathogenic Effect of TP73 Gene Variants in People With Amyotrophic Lateral Sclerosis. Neurology. doi:10.1212/WNL.0000000000012285
  • Tamamouna, V, Rahman, MM, Petersson, M, Charalambous, I, Kux, K, Mainor, H, Bolender, V, Isbilir, B, Edgar, BA, & Pitsouli, C. (2021). Remodeling of oxygen-transporting tracheoles drives intestinal regeneration and tumorigenesis in Drosophila. Nature Cell Biology, 23(5), 497-+. doi:10.1038/s41556-021-00674-1
  • Wike, C. L., Guo, Y., Tan, M., Nakamura, R., Shaw, D. K., Díaz, N., Whittaker-Tademy, A. F., Durand, N. C., Aiden, E. L., Vaquerizas, J. M., Grunwald, D., Takeda, H., & Cairns, B. R.  (2021). Chromatin architecture transitions from zebrafish sperm through early embryogenesis. Genome Res, 31(6), 981-994. doi:10.1101/gr.269860.120
  • Zhang, P., Katzaroff, A. J., Buttitta, L. A., Ma, Y., Jiang, H., Nickerson, D. W., Øvrebø, J. I., & Edgar, B. A. (2021). The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1. Proc Natl Acad Sci U S A, 118(7). doi:10.1073/pnas.2015675118

2019 

  • Deshpande, I., Liang, J., Hedeen, D., Roberts, K. J., Zhang, Y., Ha, B., Latorraca, N. R., Faust, B., Dror, R. O., Beachy, P. A., Myers, B. R., & Manglik, A. (2019). Smoothened stimulation by membrane sterols drives Hedgehog pathway activity. Nature, 571(7764), 284-+. doi:10.1038/s41586-019-1355-4
  • Feng, H. D., Magda, J. J., & Gale, B. K. (2019). Viscoelastic second normal stress difference dominated multiple-stream particle focusing in microfluidic channels. Appl Phys Lett, 115(26), 263702(1-5) doi:Artn 26370210.1063/1.5129281
  • Hanak, T. J., Libbey, J. E., Doty, D. J., Sim, J. T., DePaula-Silva, A. B., & Fujinami, R. S. (2019). Positive modulation of mGluR5 attenuates seizures and reduces TNF-alpha(+) macrophages and microglia in the brain in a murine model of virus-induced temporal lobe epilepsy. Exp Neurol, 311, 194-204. doi:10.1016/j.expneurol.2018.10.006
  • Kim, H. S., Neugebauer, J., McKnite, A., Tilak, A., & Christian, J. L. (2019). BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryoaenesis. Elife, 8. doi:ARTN e48872 10.7554/eLife.48872
  • Reidy, P. T., Yonemura, N. M., Madsen, J. H., McKenzie, A. I., Mahmassani, Z. S., Rondina, M. T., Lin, Y. K., Kaput, K., & Drummond, M. J. (2019). An accumulation of muscle macrophages is accompanied by altered insulin sensitivity after reduced activity and recovery. Acta Physiol, 226(2). doi:UNSP e13251 10.1111/apha.13251

2020

  • Dong, Z. M., Lin, E., Wechsler, M. E., Weller, P. F., Klion, A. D., Bochner, B. S., Delker, D. A., Hazel, M. W., Fairfax, K., Khoury, P., Akuthota, P., Merkel, P. A., Dyer, A. M., Langford, C., Specks, U., Gleich, G. J., Chinchilli, V. M., Raby, B., Yandell, M., & Clayton, F. (2020). Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features. Am J Pathol, 190(7), 1438-1448. doi:10.1016/j.ajpath.2020.03.005
  • Feng, H. D., Hockin, M., Zhang, S. H., Capecchi, M., Gale, B., & Sant, H. (2020). Enhanced chromosome extraction from cells using a pinched flow microfluidic device. Biomed Microdevices, 22(2). doi:ARTN 25 10.1007/s10544-020-0477-7
  • Gandelman, M., Dansithong, W., Figueroa, K. P., Paul, S., Scoles, D. R., Pulst, S. M. (2020). Staufen 1 amplifies proapoptotic activation of the unfolded protein response. Cell Death Differ. doi:10.1038/s41418-020-0553-9
  • Guo,P., Nalder,S., Okada,M., Sigala,A.P. (2020). Doxycycline has Distinct Apicoplast-Specific Mechanisms of             Antimalarial Activity. BioRxiv 2020.06.11.146407; doi: https://doi.org/10.1101/2020.06.11.146407
  • Hoffman, L.M., Smith, M.A., Jensen, C.C., Yoshigi, M. , Blankman, E., Ullman, K., Beckerle, M.C., (2020).             Mechanical Stress Triggers Nuclear Remodeling and the Formation of Transmembrane Actin Nuclear Lines With Associated Nuclear Pore Complexes. Mol Biol Cell., DOI: 10.1091/mbc.E19-01-0027
  • Lim, K., Sima, M., Stewart, R. J., & Minteer, S. D. (2020). Direct bioelectrocatalysis by redox enzymes immobilized in electrostatically condensed oppositely charged polyelectrolyte electrode coatings. Analyst, 145(4), 1250-1257. doi:10.1039/c9an02168j
  • Mahmassani, Z. S., Reidy, P. T., McKenzie, A. I., Petrocelli, J. J., Matthews, O., de Hart, N. M., Ferrara, P. J., O'Connell, R. M., Funai, K., & Drummond, M. J. (2020). Absence of MyD88 from Skeletal Muscle Protects Female Mice from Inactivity-Induced Adiposity and Insulin Resistance. Obesity, 28(4), 772-782. doi:10.1002/oby.22759
  • McKenzie, A. I., Reidy, P. T., Nelson, D. S., Mulvey, J. L., Yonemura, N. M., Petrocelli, J. J., Mahmassani, Z. S., Tippetts, T. S., Summers, S. A., Funai, K., & Drummond, M. J. (2020). Pharmacological inhibition of TLR4 ameliorates muscle and liver ceramide content after disuse in previously physically active mice. Am J Physiol-Reg I, 318(3), R503-R511. doi:10.1152/ajpregu.00330.2019
  • Than, H., Pomicter, A. D., Yan, D., Beaver, L. P., Eiring, A. M., Heaton, W. L., Senina, A., Clair, P. M., Shacham, S., Mason, C. C., Hare, T. O., & Deininger, M. W. (2020). Coordinated inhibition of nuclear export and Bcr-Abl1 selectively targets chronic myeloid leukemia stem cells. Leukemia, 34(6), 1679-1683. doi:10.1038/s41375-020-0708-1
Which Services does the HSC Cell Imaging Core provide?

We offer consultation, assisted imaging, instrument and data analysis training, and collaboration services.

How do I find the Core locations?

We currently have five major locations across campus. Please click the “Contact” tab to find the locations. The “Map” link will guide you to our office/lab within those buildings.

Does the HSC Cell Imaging Core provide services for external users?

Yes. The HSC Cell Imaging Core is a recharge center. External users from academia and industry are welcome to use our instruments by paying the service fees. We can either train you to use the instrument independently or assist you with your imaging. For more details, please contact us at Cell Imaging Support.

How do I become an HSC Cell Imaging Core user?

Please click the “New Users” icon on the main website, which provides all the necessary information. If you still have questions, please contact us at Cell Imaging Support.

How do I use the calendar to book an instrument or a core member's time?

After registering as a core user, click the "Booking" icon on the main website to reserve an instrument or a core member's time for instrument use or training.

Do I need training to use the core instrument?

Yes, authorized training is mandatory. Every user who wishes to operate the core instrument independently must complete the training provided by our core facility. Peer training within a group is not permitted and does not qualify as an alternative. The individual peer trainer or the lab will be held responsible for any issues resulting from unauthorized training. 

Do I need to book the calendar to use the microscope?

Yes, booking is mandatory. Violating this rule may result in a charge of $100 per hour for non-booked usage. Given calendar availability, last-minute bookings are possible. You can extend your time by creating a new booking before your current session ends or by notifying us if you use the microscope longer than your existing booking. 

What is the cancellation policy?

Users may modify or cancel their booking up to 12 hours before the scheduled start time. Otherwise, the hours will be charged. Exceptions apply if the cancellation is due to core-related issues, such as instrument malfunction or power outages. 

What is the hourly rate to use a core instrument or core member's time?

Please visit our core website and check the “Services” tab for the current hourly rates for all our services. 

How to I access the core instrument?

Only trained users are granted access to the room housing our core instruments. After completing the required training, core members will assist you in acquiring access to the room.