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Electron Microscopy


Electron Microscopy prepares and images specimens by transmission or scanning EM and can also do two- and three-dimensional image processing. The lab specializes in biological EM, but also works with non-biological samples. The EM Core Lab can train users in sample preparation, microscope use, and image analysis. Common EM procedures done in the lab include thin-sectioning, negative staining, and cryogenic EM (cryo-EM).

Service Rates

Requesting Services

Existing users may login directly to the Resource Scheduling System to schedule or order services. This system is cores-wide and uses University of Utah uNID authentication.

David Belnap

Facility Director

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Nancy Chandler

Senior Laboratory Specialist

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Barbie Ganser-Pornillos

Research Associate

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Willisa Liou

Research Associate

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Linda Sandaklie-Nikolova

Research Associate

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Hours of Operation

9:00 am to 5:00 pm
Monday – Friday

Recent Mentions

  1. Adriaenssens, E., B. Asselbergh, P. Rivera-Mejias, S. Bervoets, L. Vendredy, V. De Winter, K. Spaas, R. de Rycke, G. van lsterdael, F. lmpens, T. Langer and V. Timmerman (2023). Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space. Nat Cell Biol 25(3): 467- 480.10.1038/s41556-022-01074-9
  2. Ashkarran, A. A., H. Gharibi, J. W. Grunberger, A. A. Saei, N. Khurana, R. Mohammadpour, H. Ghandehari and M. Mahmoudi (2023). Sex-Specific Silica Nanoparticle Protein Corona Compositions Exposed to Male and Female BALB/c Mice Plasmas. ACS Bio Med Chem Au 1(1): 62- 73.10.1021/acsbiomedchemau.2c00040
  3. Backman, T., S. M. Latorre, L. Eads, S. Som, D. Belnap, A. M. Manuel, H. A. Burbano and T. L. Karasov (2023). A weaponized phage suppresses competitors in historical and modern metapopulations of pathogenic bacteria. bioRxiv: 2023.2004.2017.536465.10.1101/2023.04.17.536465
  4. Barnard, D. L., D. M. Belnap, P. Azadi, C. Heiss, D. S. Snyder, S. C. Bock and T. W. Konowalchuk (2022). Examining the interactions of Galahad compound with viruses to develop a novel inactivated influenza A virus vaccine. Heliyon 8(7): e09887.10.1016/j.heliyon.2022.e09887
  5. Beenken, A., G. Cerutti, J. Brasch, Y. Guo, Z. Sheng, H. Erdjument-Bromage, Z. Aziz, S. Y. Robbins-Juarez, E. Y. Chavez, G. Ahlsen, P. S. Katsamba, T. A. Neubert, A. W. P. Fitzpatrick, J. Barasch and L. Shapiro (2023). Structures of LRP2 reveal a molecular machine for endocytosis. Cell 186(4): 821- 836.e813.https://doi.org/10.1016/j.cell.2023.01.016
  6. Cooney, I., D. C. Mack, A. J. Ferrell, M. G. Stewart, S. Wang, H. M. Donelick, D. Tamayo-Jaramillo, D. L. Greer, D. Zhu, W. Li and P. S. Shen (2023). Lysate-to-grid: Rapid Isolation of Native Complexes from Budding Yeast for Cryo-EM Imaging. Bio Protoc 13(2).10.21769/BioProtoc.4596
  7. Cooney, I., H. L. Schubert, K. Cedeno, H.-J. L. Lin, J. C. Price, C. P. Hill and P. S. Shen (2023). Visualization of the Cdc48 AAA+ ATPase protein unfolding pathway. bioRxiv: 2023.2005.2013.540638.10.1101/2023.05.13.540638
  8. Gilcrease, E. B., S. R. Casjens, A. Bhattacharjee and R. Goel (2023). A Klebsiella pneumoniae NDM-1+ bacteriophage: Adaptive polyvalence and disruption of heterogenous biofilms. Front Microbial 14: 1100607.10.3389/fmicb.2023.1100607
  9. Green, Y. S., M. C. Ferreira Dos Santos, D. G. Fuja, E. C. Reichert, A. R. Campos, S. J. Cowman, K. Acuna Pilarte, J. Kohan, S. R. Tripp, E. A. Leibold, D. Sirohi, N. Agarwal, X. Liu and M. Y. Koh (2022). ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma. Oncogene 41(42): 4709- 4723.10.1038/s41388-022-02460-1
  10. Grunberger, J. W. and H. Ghandehari (2023). Layer-by-Layer Hollow Mesoporous Silica Nanoparticles with Tunable Degradation Profile. Pharmaceutics 15(3).10.3390/pharmaceutics15030832
  11. Momont, C., H. V. Dang, F. Zatta, K. Hauser, C. Wang, J. di lulio, A. Minola, N. Czudnochowski, A. De Marco, K. Branch, D. Donermeyer, S. Vyas, A. Chen, E. Ferri, B. Guarino, A. E. Powell, R. Spreafico, S. S. Yim, D. R. Salce, I. Bartha, M. Meury, T. I. Croll, D. M. Belnap, M. A. Schmid, W. T. Schaiff, J. L. Miller, E. Cameroni, A. Telenti, H. W. Virgin, L. E. Rosen, L. A. Purcell, A. Lanzavecchia, G. Snell, D. Corti and M. S. Pizzuto (2023). A pan-influenza antibody inhibiting neuraminidase via receptor mimicry. Nature 618(7965): 590-597.10.1038/s41586-023-06136-y
  12. Patel, N., M. A. Johnson, N. Vapniarsky, M. W. Van Bracklin, T. K. Williams, S. T. Youngquist, R. Ford, N. Ewer, L. P. Neff and G. L. Hoareau (2023). Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock. Sci Rep 13(1 ): 4496.10.1038/s41598-023-31374-5

Citing Our Facility

Acknowledgments

We would like to thank you for acknowledging the our facility. This recognition allows us to highlight the impact of your work and demonstrates the important contributions of our facility makes to research across the University of Utah. The recognition our core receives from your acknowledgments also aids in receiving grants and further funding for equipment and services we can provide to our users.

Self-Run Services / Instrumentation Usage:

In published papers that used instruments at our facility and notably involved staff members please use the following format:

We acknowledge (facility name) at the University of Utah for use of equipment (insert instrument/service details here), and thank (insert any notable staff member – if desired) for their assistance.

Assisted Services:

In published papers where a staff member assisted you in addition to the requested services please use the following format:

We acknowledge (facility name) at the University of Utah for use of equipment (insert instrument/service details here), and thank (insert staff member-required) for their assistance in (service provided).

Collaboration:

For publications resulting from collaborations that assisted with the methodologies, planning process and execution of your experiment in addition to equipment usage we require Co-author attribution on your publication for our facility and any staff members who provided substantial contributions to the originating project.