The Mutation Generation & Detection (MGD) Core Facility supports researchers by securing, developing, and optimizing the latest DNA nuclease technologies, reagents, and protocols for targeted genome modification. Currently, the MGD core specializes in providing customized CRISPR reagents for gene editing in multiple model systems, including but not limited to M. musculus, D. rerio, D. melanogaster, C. elegans, S. cerevisiae and mammalian cell lines. Beyond reagent production, the MGD Core collaborates with other University of Utah core facilities to generate genetically modified mouse models and cell lines. The MGD Cores also provides custom genotyping services including High Resolution Melt Analysis (HRMA), CRISPR validation services, homology directed repair donor template synthesis, custom cloning services and targeted sequencing services.
8:00 am to 5:00 pm
Monday – Friday
We would like to thank you for acknowledging the our facility. This recognition allows us to highlight the impact of your work and demonstrates the important contributions of our facility makes to research across the University of Utah. The recognition our core receives from your acknowledgments also aids in receiving grants and further funding for equipment and services we can provide to our users.
In published papers that used instruments at our facility and notably involved staff members please use the following format:
In published papers where a staff member assisted you in addition to the requested services please use the following format:
For publications resulting from collaborations that assisted with the methodologies, planning process and execution of your experiment in addition to equipment usage we require Co-author attribution on your publication for our facility and any staff members who provided substantial contributions to the originating project.