Nuclear Magnetic Resonance

This NMR core facility offers services, expertise, and collaboration for the research community at the University of Utah, other Utah academic institutions, and for-profit companies. Our staff is extremely helpful and has significant experience in characterizing small molecules, natural products, nucleic acids, carbohydrates, and proteins using NMR. Our preferred business model is for users to become skilled and independent users of the NMR facility. We train new users, or help experienced but out-of-practice users to brush up their skills, with the goal of user independence. On a limited basis, we will also record and analyze NMR data for a staff service charge.

We provide convenient access to five high field NMR spectrometers (400, 500, 600, 800, and 900 MHz instruments; see Equipment below) located on the University of Utah Health Sciences campus and the University of Colorado-Boulder and -Denver campuses. The 600, 800, and 900 instruments are equipped with state-of-art cryogenic HCN probes that provide maximum sensitivity. The 800 and 900 are state-of-art NMR consoles while the 400, 500, and 600 are older but still fully capable for all NMR requirements. The facility has several Linux workstations and a considerable number of implemented NMR software programs (member of SBGrid; for data processing, data analysis, and structure calculation.












Instruments Rates**
Academic (U of U) Academic (Off-Site) For-Profit
Mercury 400 (Skaggs Rm 2) $8/hr (7AM-7PM) / $4/hr (7PM-7AM) $9/hr $12.50/hr
Inova 500 (BPRM Rm 50) $8/hr (7AM-7PM) / $4/hr (7PM-7AM) $9/hr $12.50/hr
Inova 600 (BPRB Rm 50) $8/hr (7AM-7PM) / $4/hr (7PM-7AM) $9/hr $12.50/hr
  • NMR data collection and analysis with or without staff collaboration
  • NMR training for individuals and groups
  • Formal courses in NMR spectroscopy
  • If staff assistance is required the fee is increased by $25/hr.
  • Varian Mercury 400 MHz NMR (University of Utah, SK H)
  • Varian Inova 500 MHz NMR (University of Utah, BPRB)
  • Varian Inova 600 MHz NMR with HCN cryogenic probe (University of Utah, BPRB)
  • DD2 800 MHz NMR with HCN cryogenic probe (University of Colorado-Boulder)
  • DD2 900 MHz NMR with HCN cryogenic probe (University of Colorado-Denver)
General Safety Guidelines & Usage Rules

Please take the time to read the following material. There are only a few rules, but we expect them to be followed.

  1. No food or drinks are allowed in the lab.
  2. No radioactive, or highly dangerous biological or chemical samples are allowed in the lab.
  3. Working with chemicals or preparing samples on the computer desks is not allowed.
  4. Gloves are not allowed when typing on the keyboards or using the spectrometers.
  5. Magnetic objects, whether small or large may constitute a hazard to the instrument and to the user and are not allowed near the magnets.
  6. Samples broken outside the magnet should be thoroughly cleaned up and reported to the staff. This includes everything that came into contact with the sample: the working surface, desk, depth gauge, spinner, etc. Insert the sample tube into the spinner above a cleanable surface.
  7. Samples broken inside the magnet should be reported to the staff immediately, and a note stating that the instrument is out of order should be visibly posted on the computer keyboard.
  8. Superconducting magnets may quench for a variety of reasons. During a quench, the liquid helium inside the magnet’s cryostat is boiled off very rapidly, resulting in a fast and massive release of helium gas along with a loud sound. Although helium is not toxic, it will reduce the oxygen concentration in the lab possibly leading to disorientation, loss of conscience and suffocation. If you observe a large exhaust of white gas coming out from one of the magnets, or a large condensation cloud at the lab’s ceiling, vacate the lab immediately and notify the staff. Wait at least one hour to re-enter the lab.
  9. The NMR center is a multi-user facility; and all users must be considerate of the sign-up rules in order for everyone to be accommodated. Recurrent violation of the rules by any individual will not be tolerated and could result in loss of NMR privileges.
  10. Use of the spectrometers is restricted to U of Utah’s faculty, graduate students, postdoctoral fellows and other authorized persons after successful training and approval. Undergraduates engaged in long term independent research projects under faculty direction will be trained on these instruments upon their supervisor’s request.
  11. Only persons who have received or are receiving training, or are otherwise authorized are allowed in the lab. Users with pacemakers or other medical implants are not allowed near the magnets and must consult with the staff for approval.
  12. Haphazard experimentation with the NMR hardware will not be tolerated under ANY circumstance; violation of this policy will result in immediate and permanent loss of NMR privileges. Users are not authorized to change probes or modify hardware except as instructed during training or after proper authorization. If there is trouble with any of the NMR instruments, ask the NMR staff for help. Report all hardware or software malfunctions as soon as possible.
  13. It is the responsibility of all users to learn the capabilities of each instrument to avoid damage and maximize efficient use of the NMR hardware.
  14. Be considerate of other NMR users when scheduling measurement time.
Hours of Operation

Monday-Friday 8am-6pm


50 BRRB, Bldg. 570
20 S 2030 E
Salt Lake City, UT  84112


Jack Skalicky, Ph.D., NMR Core Director and Res. Associate Professor of Biochemistry
Office: 801-585-7363
Lab: 801-585-9658

Dennis Edwards, RF Technician; 35+ years of NMR hardware repair

New Equipment

  • The Closed Cycle Chiller (CCC) cold head was replaced in FY 2018 (this service is required every 2-3 years for optimal operation of the 600 cryoprobe)
  • Facilities added a new ooling loop in BPRB. This upgrade now provides reliable cooling of the CCC helium compressor

New Services

  • The NMR Facility did not implement additional services in FY21


  • VP of Health Sciences Support: $70,000
  • FY21 revenue generated from services: $38,678
  • FY21 expenses: $108,444
  • FY21 revenue: $108,678



Last meeting date: April 2013

  • Darrell Davis, Professor, College of Pharmacy
  • Wesley Sundquist, Professor, Department of Biochemistry
  • Eric Schmidt, Professor, College of Pharmacy

Revenue by Campus Affiliation:


Revenue by Departments:


Top Users

1 Schmidt, Eric NIH, US Army Medical Research
2 Franzini, Raphael Department
3 Vaporsens, Inc Commercial
4 Winter, Jaclyn Department, Gordon & Betty Moore Foundation
5 Echelon Biosciences Commercial
6 Chou, Hung-Chieh NIH, US Army Medical Research, Juvenile Diabetes Research Foundation
7 Haygood, Margo Department
8 Barrios, Amy Department
9 McIntosh, Michael NIH
10 Kramer, Jessica Department, NSF