Publications

Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J. A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila and humans. Science. 2012. Jul 6;337(6090):96-100. Epub 2012 May 24. PMID:22628558

Cox HD, Smeal SJ, Hughes CM, Cox JE, Eichner D. Detection and in vitro metabolism of AOD9604. Drug Test Anal. 2014 Sep 10. doi: 10.1002/dta.1715.

Cox JC, Williams S, Grove K, Lane RH, Aagaard-Tillery KM. A maternal high fat diet is accompanied by alterations in the fetal primate metabolome. Am J Obstet Gynecol. 2009 Sep; 201(3):281.e1-9.

Deering-Rice CE, Romero EG, Shapiro D, Hughen RW, Light AR, Yost GS, Veranth JM, Reilly CA. Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP. Chem Res Toxicol, 2011 Jun; 24(6):950-9.

Donia MS, Fricke WF, Partensky F, Cox JE, Elshahawi SI, White JR, Phillippy AM, Schatz MC, Piel J, Haygood MG, Ravel J, Schmidt EW. Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis. Proc Natl Acad Sci USA. 2011. Dec 20;108(51):E1423-32.

Fullmer TM, Pei S, Zhu Y, Sloan C, Manzanares R, Henrie B, Pires KM, Cox JE, Abel ED, Boudina S. Insulin suppresses ischemic preconditioning-mediated cardioprotection through Akt-dependent mechanisms. J Mol Cell Cardiol. 2013 Nov;64:20-9.

Fung C, Brown A, Cox JE, Callaway C, McKnight R, Lane R. Novel thromboxane A2 analog-induced IUGR mouse model. J Dev Orig Health Dis. 2011 2(5): 291-301.

Gleason JE, Corrigan DJ, Cox JE, Reddi AR, McGinnis LA, Culotta VC. Analysis of hypoxia and hypoxia-like states through metabolite profiling. PLoS One. 2011; 6(9):e24741.

Hintze KJ, Cox JE, Rompato G, Benninghoff AD, Ward RE, Broadbent J, Lefevre M. Broad scope method for creating humanized animal models for animal health and disease research through antibiotic treatment and human fecal transfer. Gut Microbes. 2014 Mar 5;5(2).

Huang J, Simcox J, Mitchell TC, Jones D, Cox J, Luo B, Cooksey RC, Boros LG, McClain DA. Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice. FASEB J. 2013 Jul;27(7):2845-54. doi: 10.1096/fj.12-216929. Epub 2013 Mar 20.

Kaadige MR, Looper RE, Kamalanaadhan S, Ayer DE. Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity. Proc Natl Acad Sci USA. 2009 Sep 1;106(35):14878-83.

Kannan S, Muthusamy VR, Whitehead KJ, Wang L, Gomes AV, Litwin SE, Kensler TW, Abel ED, Hoidal JR, Rajasekaran NS. Nrf2 Deficiency Prevents Reductive Stress Induced Hypertrophic Cardiomyopathy. Cardiovasc Res. 2013 Jun 12. [Epub ahead of print]

Kohl KD, Weiss RB, Cox J, Dale C, Denise Dearing M. Gut microbes of mammalian herbivores facilitate intake of plant toxins. Ecol Lett. 2014 Oct;17(10):1238-46.

Lin Z, Falkinham JO 3rd, Tawfik KA, Jeffs P, Bray B, Dubay G, Cox JE, Schmidt EW. Burkholdines from Burkholderia ambifaria: Antifungal Agents and Possible Virulence Factors. J Nat Prod. 2012 Sep 18. [Epub ahead of print] PMID:22988812

Lin Z, Torres JP, Ammon MA, Marett L, Teichert RW, Reilly CA, Kwan JC, Hughen RW, Flores M, Tianero MA, Peraud O, Cox JE, Light AR, Villaraza AJL, Haygood MG, Concepcion GP, Olivera BM, Schmidt EW. A baceterial source for mollusk pyrone polyketides. Chem & Biol. 2013 Jan; 20(1):73-81.

McClain DA, Abuelgasim KA, Nouraie M, Salomon-Andonie J, Niu X, Miasnikova G, Polyakova LA, Sergueeva A, Okhotin DJ, Cherqaoui R, Okhotin D, Cox JE, Swierczek S, Song J, Simon MC, Huang J, Simcox JA, Yoon D, Prchal JT, Gordeuk VR. Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism. J Mol Med (Berl). 2012 Sep 27. PMID: 23015148

Na U, Yu W, Cox JE, Bricker DK, Brockmann K, Rutter J, Thummel CS, Winge DR. The LYR Factors SDHAF1 and SDHAF3 Mediate Maturation of the Iron-Sulfur Subunit of Succinate Dehydrogenase. Cell Metab. 2014 Jun 18. pii: S1550-4131(14)00222-8.

Palanker, L, Tennessen JM, Lam G,Thummel CS. Drosophila HNF4 regulates lipid mobilization and beta-oxidation. Cell Metab. 2009 Mar;9(3):228-39.

Price, C. T., Al-Quadan, T., Santic, M., Rosenshine, I., Abu Kwaik, Y. Host Proteasomal Degradation Generates Amino Acids Essential for Intracellular Bacterial Growth. 2011, Science 334, 1553-1557.

Ridges S, Joshi D, Heaton WL, Choi H, Eiring A, Batchelor L, Choudhry P, Manos EJ, Sofla H, Sanati A, Welborn S, Agarwal A, Spangrude G, Miles RR, Cox JE, Frazer JK, Deininger M, Balan K, Sigman M, Müschen M, Perova T, Johnson R, Montpellier B, Guidos CJ, Jones D, Trede NS. Zebrafish screen identifies novel compound with selective toxicity against leukemia. Blood. 2012 Jun 14;119(24):5621-31.

Shakoury-Elizeh M, Protchenko O, Berger A, Cox J, Gable K, Dunn TM, Prinz WA, Bard M, Philpott CC. The metabolic response to iron deficiency in Saccharomyces cerevisiae. J Biol Chem. 2010 May; 285(19):14823-33.

Shakya A, Cooksey RC, Cox JE, Wang V, McClain DA, Tantin D. Oct1 loss of function induces a coordinate metabolic shift that opposes tumourigenicity. Nat Cell Biol. 2009 Mar;11(3):320-7.

Shibayama J, Taylor TG, Venable PW, Rhodes NL, Gil RB, Warren M, Wende AR, Abel ED, Cox JE, Spitzer KW, Zaitsev AV. Metabolic determinants of electrical failure in ex-vivo canine model of cardiac arrest: evidence for the protective role of inorganic pyrophosphate. PLoS One. 2013;8(3):e57821. doi: 10.1371/journal.pone.0057821. Epub 2013 Mar 8.

Shibayama J, Taylor TG, Venable PW, Rhodes NL, Gil RB, Warren M, Wende AR, Abel ED, Cox JE, Zaitsev AV. Metabolic predictors and determinants of early electrical failure in ex-vivo canine model of long-duration ventricular fibrillation. PLoS One. 2013;8(3):e57821. doi: 10.1371/journal.pone.0057821. Epub 2013 Mar 8.

Stoltzman CA, Kaadige MR, Peterson CW, Ayer DE. MondoA senses non-glucose sugars: regulation of thioredoxin-interacting protein (TXNIP) and the hexose transport curb. J Biol Chem. 2011 Nov 4;286(44):38027-34. Epub 2011 Sep 9.

Tennessen JM, Baker KD, Lam G, Evans J, Thummel CS. The Drosophila estrogen-related receptor directs a metabolic switch that supports developmental growth. Cell Metab. 2011 Feb; 13(2):139-48.

Tennessen JM, Barry WE, Cox JE, Thummel CS. Methods for studying metabolism in Drosophila. Methods. 2014 Jun 15;68(1):105-15.

Tennessen JM, Bertagnolli NM, Evans J, Sieber MH, Cox JE, Thummel CS. Coordinated Metabolic Transitions During Drosophila Embryogenesis and the Onset of Aerobic Glycolysis. G3 (Bethesda). 2014 Mar 12;4(5):839-50.

Van Vranken JG, Bricker DK, Dephoure N, Gygi SP, Cox JE, Thummel CS, Rutter J. SDHAF4 Promotes Mitochondrial Succinate Dehydrogenase Activity and Prevents Neurodegeneration. Cell Metab. 2014 Jun 18. pii: S1550-4131(14)00222-8.

Wang L, Lam G, Thummel CS. Med24 and Mdh2 are required for Drosophila larval salivary gland cell death. Dev Dyn. 2010 Mar;239(3):954-64.

Wright JJ, Kim J, Buchanan J, Boudina S, Sena S, Bakirtzi K, Ilkun O, Theobald HA, Cooksey RC, Kandror KV, Abel ED. Mechanisms for increased myocardial fatty acid utilization following short term high fat feeding. Cardiovasc Res. 2009 May 1;82(2):351-60.