This page is intended to link a few example papers of how Ion Torrent NGS data is being used in research. They are here for your convenience and are not intended to be a comprehensive list of publications. Please feel free to follow the links to the papers and peruse them to help determine if the Ion Torrent platform would be useful for your research. Please feel free to inform me of other publications using Ion Torrent that might be beneficial to the larger research community.
Comparison Papers Ion Torrent and Illumina
The new sequencer on the block: comparison of Life Technology’s Proton sequencer to an Illumina HiSeq for whole-exome sequencing. Boland JF, Chung CC, Roberson D, Mitchell J, Zhang X, Im KM, He J, Chanock SJ, Yeager M, Dean M. Hum Genet. 2013 Oct;132(10):1153-63. doi: 10.1007/s00439-013-1321-4. Epub 2013 Jun 12.
ChipSeq on Ion Torrent
Semiconductor-based DNA sequencing of histone modification states. Cheng CS, Rai K, Garber M, Hollinger A, Robbins D, Anderson S, Macbeth A, Tzou A, Carneiro MO, Raychowdhury R, Russ C, Hacohen N, Gershenwald JE, Lennon N, Nusbaum C, Chin L, Regev A, Amit I. Nat Commun. 2013;4:2672. doi: 10.1038/ncomms3672.
SNP Discovery on Ion Torrent
High-throughput SNP discovery in the rabbit (Oryctolagus cuniculus) genome by next-generation semiconductor-based sequencing. Bertolini F, Schiavo G, Scotti E, Ribani A, Martelli PL, Casadio R, Fontanesi L. Anim Genet. 2014 Jan 21. doi: 10.1111/age.12121. [Epub ahead of print]
Ion Torrent Sequencing from FFPE Samples
Molecular diagnostic profiling of lung cancer specimens with a semiconductor-based massive parallel sequencing approach: feasibility, costs, and performance compared with conventional sequencing. Endris V, Penzel R, Warth A, Muckenhuber A, Schirmacher P, Stenzinger A, Weichert W. J Mol Diagn. 2013 Nov;15(6):765-75. doi: 10.1016/j.jmoldx.2013.06.002. Epub 2013 Aug 21.
Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study.Li S, Tighe SW, Nicolet CM, Grove D, Levy S, Farmerie W, Viale A, Wright C, Schweitzer PA, Gao Y, Kim D, Boland J, Hicks B, Kim R, Chhangawala S, Jafari N, Raghavachari N, Gandara J, Garcia-Reyero N, Hendrickson C, Roberson D, Rosenfeld J, Smith T, Underwood JG, Wang M, Zumbo P, Baldwin DA, Grills GS, Mason CE.
Nat Biotechnol. 2014 Sep;32(9):915-25. doi: 10.1038/nbt.2972. Epub 2014 Aug 24.